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- Endometriosis Institute -

 

Endometriosis Institute of Los Angeles
New Location!
9301 Wilshire Blvd. - Suite 208
Beverly Hills, California 90210
Phone: 213-640-2555 - Fax: 310-278-7599


Endometriosis has been an enigmatic disease since it's first diagnosis in the mid-19th century. Since that time, there has been a continuous stream of information and discoveries. But up until today, there are still many unanswered questions. The questions which are most important are:

Why does Endometriosis strike some women and does not others?

Why do some women with extensive Endometriosis, have hardly any symptoms while others with minimal disease have severe symptoms?

What is the best way to diagnose and treat Endometriosis?

What exactly is the mechanism for reducing fertility in women who have Endometriosis?


The doctors at the Tyler Medical Clinic, which was founded in the early 40's in West Los Angeles and primarily geared to diagnosis and treatment of infertility, have been puzzled by this disease for many years. A significant portion of the patients coming to the Tyler Medical Clinic are suspected or proven to have Endometriosis. Recent statistics indicate that infertility problems can be traced to Endometriosis in one out of four couples. Because of the keen interest in this particular area, the physicians at the Tyler Medical Clinic have been involved in the research on the etiology of Endometriosis and in numerous studies investigating the best and most effective ways to control the disease or possibly eradicate it altogether. Because of this interest, the Endometriosis Institute of Los Angeles was formed several years ago. The primary interest of this institution is obviously the diagnosis, treatment and the study of Endometriosis.

Some of the historical data of Endometriosis therapy dates back to the '50's when increasing doses of oral contraceptives had been used in hopes of controlling the disease. The next method of treatment used Progesterone and synthetic Progestin to achieve better results. These particular medications had worked to some degree but the side effects were significant and forced some of the patients to discontinue therapy because the symptoms of the disease were easier to tolerate than the side effects of the medication.

By the early 70's, our physicians were involved in the last part of the clinical investigations of Danazol (Danocrine) prior to FDA for approval. At that time, we were quite impressed by the effectiveness of this medication earmarked for the treatment of Endometriosis. The patients treated in the early 70's are still followed now when in spontaneous menopause.

Development in infertility surgery and primarily Laparoscopy was another strong weapon in the control or eradication of Endometriosis. The examination of the abdominal cavity and the pelvis became simpler. Laparoscopy can be done as an outpatient procedure on an "in and out" basis, it does not incapacitate the patient for extended lengths of time and thus is much more acceptable. Following introduction of Danocrine and Laparoscopy, several other medications specifically designed for treatment of Endometriosis entered the market and gave the physician even more choices to deal with this difficult disease. Understanding as well as therapeutic armamentarium has improved significantly.

Our studies of various medications indicate that if the patient with Endometriosis was diagnosed and treated properly, approximately 1/3 of them will achieve a complete cure, 1/3 might have a return of Endometriosis after several years but no symptoms, and 1/3 might experience the return of Endometriosis as well as symptoms. The usual time of relief of symptoms after proper therapy is three to five years. Patients who experience return of the disease and symptoms can be successfully retreated and will gain another chance of cure or asymptomatic existence.

As noted above, our other interest is diagnosis and treatment of infertility. Several symptom free years following completion of therapy give the patient an excellent chance to conceive. Of course, pregnancy will favorably affect the disease and increase the chances of complete and satisfactory cure. Our more than three decades of experience indicate that if patients are treated properly, the chance to conceive is approximately 72%. Whereas if the therapy is not properly administered, incomplete or there was no therapy at all, the chances of conception are approximately 9%. That is a compelling reason to investigate the best therapeutic options.

The physicians and other members of the Endometriosis Institute of Los Angeles have had many years of experience in the diagnosis, medical and surgical treatment of Endometriosis and understand the many problems of the women who suffer from this disease.

 


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Copyright 2001 Institute for Reproductive Medicine and Genetic Testing
Last modified: 04/02/04