- Genetic Diseases -
Fast Facts on Genetic Disorders and PGD
According to the March of Dimes:
1 out of every 100 Americans is born
with a serious genetic defect.
Approximately 20,994 California babies
are born with a birth defect annually.
There are more than 4,000 known birth
Birth defects are the leading cause of
death in the first year of life and account for more than 1 in 5
For babies born with birth defects in
1992, estimated lifetime costs total 48 billion.
According to the National Center for
Health Statistics, in 1995, 11.6% or 453,722 babies were born to
women over 35.
From the book Planning Your Pregnancy
and Birth by the American College of Obstetrics and Gynecologists:
All human cells have 46 chromosomes each
possessing between 50 million and 250 million base pairs of DNA
molecules in each chromosome.
A gene is a segment of DNA that is coded
to pass along a certain trait.
The body has about 50,000 to 100,000
There is a 1 in 4 chance of passing a
genetic disorder on to the child if both partners carry the same
recessive disorder. A 1 in 2 chance if either carries a dominant
In the United States:
About 1 in 625 African Americans has
sickle cell disease and 1 in 10 are carriers.
1 in 2,500 Caucasians have cystic
fibrosis and 1 in 25 are carriers.
About 1 in 800 babies is born with
Facts from the American Society of
About 7% of still births and neonatal
deaths have chromosomal abnormalities.
Recurrent miscarriages may be due to
Preimplantation Genetic Diagnosis - PGD
was first performed in 1989.
Nearly 200 babies have been born
following the first PGD.
Over 200 disorders could potentially be
prevented by using PGD to screen gender based disorders.
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Copyright © 2001 Institute
for Reproductive Medicine and Genetic Testing